Home » News Flash » The baseless fabric of this vision. Sir, I am vexed. It is not obvious and the promoters of serrapeptase do not offer a mechanism. Sir, I am vex'd; It has a very classic TV feel with a theme song that could have been pulled right out of the 1950s. Or, if that’s not your mindset, hook up with someone who is an entrepreneur. Hardly anyone in biotech becomes an entrepreneur before they’re in their 30’s or 40’s; it’s not like IT where you can start young. Any idea when I might get a drug or two (not the 5 that I take now which are worthless for what it’s worth) that will enable me to walk without feeling like I’m on fire, the wind is out to get me, or I am getting stung by 30 really pissed off hornets all at once? And like the baseless fabric of this vision, The cloud-capp’d tow’rs, the gorgeous palaces, The solemn temples, the great globe itself, Yea, all which it inherit, shall dissolve, And, like this insubstantial pageant faded, Leave not a rack behind. Some unsolicited advice to pharma investors…if the company CEO is an economist, accountant, sales guy….wannabe UK House of Lords aspirant, hedge-fund manager, ex-McKinsey guy…store your money under the mattress. Told by an idiot, full of sound and fury, Interesting that my attempts at researching inflammation got me here in the first place. British Broadcasting Company (BBC):To be the most creative organization in the world 4. Not long ago, almost all of R&D exited the North Carolina site at RTP. And, like the baseless fabric of this vision, The cloud-capp’d towers, the gorgeous palaces, The solemn temples, the great globe itself, Yea, all which it inherit, shall dissolve And, like this insubstantial pageant faded, Leave not a rack behind. baseless adj : without a basis in reason or fact; "baseless gossip"; "the allegations proved groundless"; "idle fears"; "unfounded suspicions"; "unwarranted jealousy" [syn: groundless, idle, unfounded, unwarranted] Dictionary source: hEnglish - advanced version Within his therapeutic area (Pulmonary) he tends to be skeptical of most ideas from the US while being very protective of his UK resources, in particular the chemists in his line. 152 The cloud-capp'd towers, the gorgeous palaces, 153 The solemn temples, the great globe itself, 153. the great globe itself: all the world. And, like the baseless fabric of a vision, Leave not one wreck behind." The hand that mocked them and the heart that fed: They’re much more interested in clinical assets with a clear 1-3 year exit strategy. We are such stuff As dreams are made on, and our little life Is rounded with a sleep. Good idea in theory… but difficult in practice. adj.). --Sir P. Sidney. The cloud-capp’d tow’rs, the gorgeous palaces, You can be absolutely certain that senior management is the ONLY part of a company which will never be outsourced. At the end of the day, the drug discovery industry is disregarding the contributions of a motivated, talented and experienced sizable group of colleagues, who provide a unique perspective (at the molecular level) without which success is much less likely and more random. If I had more than the gift of gab, perhaps esp….I’d have become my own chemist years back, before the RSD and all, ya’ll. Alas, all planning! As a great man once said, “success is the ability to go from one failure to another with no loss of enthusiasm.”, Yep – full marks. This is one of Shakespeare's most beautiful speeches and its laden with hidden gems. There is a quote from Macbeth (Act 5, scene 5) that may possibly be appropriate: “To-morrow, and to-morrow, and to-morrow, And, like the baseless fabric of this vision, The cloud-capp'd towers, the gorgeous palaces, The solemn temples, the great globe itself, Yea, all which it inherit, shall dissolve, And, like this insubstantial pageant faded, Leave not a rack behind. Nice attempt to defend GSK (I remember Chris Viebacher, Accounting Genius drug discoverer vehemently defending Avandia) but the facts are against you. That includes people who discovered most of their virology drugs (mostly NC scientists), oncology drugs (which they then sold) (mostly NC scientists), and many of the best UK scientists who discovered the multitude of drugs there in Neuro, asthsma, anti-infectives, and other areas. GSK is undeniably endowed with a best-of-breed team of chemists so it is understandably keen to motivate, develop and retain them. Of course the author would discuss the loss of jobs in the UK because it is under his nose every day. Prospero: These our actors, As I foretold you, were all spirits and Are melted into air, into thin air; And, like the baseless fabric of this vision, The cloud-capped towers, the gorgeous palaces, The solemn temples, the great globe itself, Yea, all which it inherit, shall dissolve…. Long time no see! Despite what a few embittered former employees might say, the company has finally got its mojo back! -richer Yet when we measure time in years rather than hours, we can see that most of the real … Anyway, I had a wonderful year overthere, so even if the “best chemists” are gone, those left are still excellent and I learnt a lot ! For example, in 2015, one third of new drugs approved in the US by the Food and Drug Administration (FDA) were antibodies, peptides or enzymes, compared with about a quarter in 2014 (Ref #3 C&EN). It is not yet 20 years since Hong Kong was handed back to China, yet many of the old symbols of British rule have entirely faded. I do, however, give the author credit for this ending: Ultimately, however, the success of the model will be judged by the destination, which in our industry tends to be some 10 years after the medicinal chemistry costs are spent. And, like the baseless fabric of this vision, The cloud-capp'd towers, the gorgeous palaces, The solemn temples, the great globe itself, Ye all which it inherit, shall dissolve And, like this insubstantial pageant faded, Leave not a rack behind. None of it sounds particularly bad on paper, but a person of cynical bent would note that sounding good on paper is a major design feature of all these things. We know what that means. Baseless fabric means "substance without foundation," which poetically translates in this context to an artifice or contrivance. I assume most readers consider this the correct one? And, like the baseless fabric of this vision, The cloud-capp’d towers, the gorgeous palaces, The solemn temples, the great globe itself, Yea, all which it inherit, shall dissolve And, like this insubstantial pageant faded, Leave not a rack behind. And, like the baseless fabric of this vision, The cloud-capped towers, the gorgeous palaces, The solemn temples, the great globe itself, Yea, all which it inherit, shall dissolve; And, like this insubstantial pageant faded, Leave not a rack behind. A three to seven day tour of Hong Kong is still the most frequent way those living in rural China see the “outside world”. 4. a. And, like this insubstantial pageant faded, Hence, something unreal or imaginary; a creation of fancy. At one point the ratio biologists/chemists started increasing, the healthy relationship between them deteriorated, and eventually medicinal chemists were thrown under the bus. As dreams are made on; and our little life. He has little to lose at GSK in his current position as he’s not likely to go further up the line unless they’d remake traditional technical departments instead of focusing on therapy area structures. We are such stuff As dreams are made on; and our little life Is rounded with a sleep. The productive confusion of the command reveals how, in Prospero’s mind, both the cloak and Miranda possess both human and material properties. Its attractiveness remains its liberal tax laws and ease of setting up corporate entities, but walk outside the smart offices and designer malls of Admiralty and the waterfront tourist quarters and there before you the city is culturally imploding. -less likely to take the level of bullsh*t I put up with in med chem roles Even in a tight jobs market the “very best” people tend to get multiple offers. But once you’ve done it you wonder why you ever thought being just another cog in a wheel was a life worth living. Near them, on the sand, This was when your R&D was most productive. The next problem is how to attract the “very best” people. The local population is largely evident by their frequent offhanded surliness and snobbery against any mandarin-speaking tourist that crosses their path. 401Ks and CEO windfalls all sound nice….I’d like to be able to walk past 2pm every day. Instead of whining, take a risk and become entrepreneurs. Google Marty Freed and Zarifa in the NY Times to see excerpts from internal emails. Very few people are even in charge for that long, for that matter, and the next set of people will have their own ideas about things should be run. The revelation from God had two purposes. And, like the baseless fabric of this vision,/ The cloud-capp'd towers, the gorgeous palaces,/ The solemn temples, the great globe itself, /Yea, all which it shall inherit, shall dissolve." -beginning to be convinced that contemporary molecule-metric med-chem was beginning to turn into a cargo-cult with Lipinski as it’s patriarch. (Act 4 Scene 1, Lines 147). All rights Reserved. If people start a family assuming they’re going to be around for it, starting a business is probably not compatible (as from C+E News, “And even being your own boss doesn’t always help. Combined with the word vision (here in its denotation as "supernatural or imaginary appearance"), referring to the pageant, it continues the theme of theatrical magic. The Hindu life is related to this cosmology And the objective of life is of course in the end to wake up from the dream When you've had enough And so, the dreaming process is called sometimes Samsara This is the group that purchased Sirtris (-$1B) after their own internal diligence team told them not to; exited PCSK9 (-$1B per year, we know now); exited anti-thrombotics (also likely -$1B per year); greenlighted darapladib (-$1B). --Locke. Like the Baseless Fabric of this Vision (graphite, charcoal, pencil & chalk on paper, 30” x 41”, 2009) And, like the baseless fabric of this vision, The cloud-capp'd towers, the gorgeous palaces, ... What is the meaning of the masque and anti-masque in Shakespeare's play The Tempest? 2. a. Steve, that sounds great in theory but with medchem you probably need to hit your mid-thirties before you come close to any degree of mastery – and by that time, probably have financial and personal commitments that make entrepreneurship hard, if not almost impossible. Finally, where there have been large controlled clinical trials, it was not better than placebo. The lone and level sands stretch far away. Remember, this was in the era of Japan Is Coming to Rule the World, itself an interesting artifact of long-range thinking: if you’d asked a bunch of consultants back then to predict Japan’s economy over the next 25 years, I’m pretty sure that what really happened (flatter than a sushi mat) would never have made the list, not even in the backup slides. (IV.i. Also, “The best lack all conviction while the worst are full of passionate intensity” might be relevant here. 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All sound nice….I ’ D like to be able to walk past 2pm every day his nose every.. Despite what a few trials involving anti TNF treatments for RSD CrossRef COUNTER.
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